* Price for purchase of 3 months supply.
Estradiol is offered on a quarterly plan only:
Online medical intake and provider review
Prescription (if eligible)
Medication delivery to your door
Ongoing care and secure messaging
No insurance required
Estradiol is commonly prescribed for perimenopause and menopause symptoms, including hot flashes, night sweats, vaginal dryness, mood changes, and sleep disturbances.
Yes. Estradiol is available as a gel, patch, or tablet. Your provider will help determine the most appropriate option for you.
Commonly prescribed to help reduce hot flashes, night sweats, and vaginal dryness during perimenopause and menopause.
May help ease mood changes, sleep disruption, brain fog, and fatigue associated with estrogen imbalance.
Transdermal estrogen bypasses first-pass liver metabolism and is often considered when evaluating cardiovascular risk factors.
Estradiol is delivered gradually to help maintain more consistent hormone levels without daily dosing.
Answer a few quick questions to personalize your treatment.
A licensed provider reviews your intake and prescribes treatment if eligible.
Medication is shipped straight to your door with expedited shipping.
All medication is dispensed by licensed U.S.pharmacies that meet strict safety and quality standards.
I’ve lost 20 pounds in 90 days. My provider helped me find the right treatment, the support team was responsive. Everything from refills to provider messaging is handled right in their app.
Miami, FL
218 lbs
198 lbs
-20 lbs
3 mo
I wasn’t thinking about food all day anymore. Within a few weeks, my cravings were under control and I started seeing results.
Dallas, TX
201 lbs
171 lbs
-30 lbs
4 mo
Long days on the road made it hard to stay on track. Within weeks, my appetite was under control and the weight started coming off.
Charlotte, NC
222 lbs
177 lbs
-45 lbs
8 mo
The online visit took just a few minutes, and I could message my provider in the App whenever I needed help.
New York, NY
208 lbs
183 lbs
-25 lbs
3 mo
I’m not constantly thinking about food anymore, and the weight is finally coming off. I feel healthier, more confident, and more like myself every week.
Richmond, VA
212 lbs
193 lbs
-19 lbs
3 mo
I tried diets before, but the results never lasted. The provider helped me find the right treatment, and now I’m finally losing weight every week.
Hoover, AL
246 lbs
211 lbs
-35 lbs
6 mo
I put off dealing with my weight for years. The process was simple, the support was excellent, and now I’m steadily losing weight every week.
Santa Barbara, CA
223 lbs
201 lbs
-22 lbs
5 mo
He & She MD is a modern telehealth clinic offering treatments across Weight Loss, Longevity, Hormone Therapy, and Performance Health. Getting started is simple: complete a quick 5-minute medical quiz, and a licensed U.S. clinician will review your information. If appropriate, your medication is shipped directly — and discreetly — to your door.
Our care process is designed to make treatment fast, safe, and convenient:
💳 You are only charged if the medication is prescribed.
(If you are not a candidate, you pay nothing.)
He & She MD provides personalized care across six core treatment categories, with every treatment plan reviewed by a licensed healthcare provider and customized to your individual health goals.
Weight Loss
Medical weight loss programs featuring GLP-1 medications, including compounded Semaglutide and Tirzepatide (where appropriate), as well as FDA-approved brand medications such as Wegovy®, Ozempic®, Zepbound®, and Mounjaro® when clinically appropriate and available.
Longevity
Advanced wellness therapies designed to support healthy aging, energy, recovery, and overall vitality, including NAD+, Glutathione, Sermorelin, and other longevity-focused peptide therapies.
Hormone Therapy
Personalized hormone optimization for men and women, including treatments such as testosterone support, estradiol, progesterone, and other evidence-based hormone therapies designed to restore balance and improve quality of life.
Performance Health
Treatments designed to support men’s health, energy, strength, recovery, and sexual performance, including Enclomiphene, and Testosterone Replacement Therapy (when appropriate), and other physician-directed therapies.
Hair Growth
Personalized hair restoration treatments for both men and women, including oral and topical medications such as Finasteride, Minoxidil, combination therapies, and other clinically appropriate hair loss solutions.
Sexual Health
Discreet, evidence-based treatments for sexual wellness, including erectile dysfunction therapies, libido support, and other personalized solutions including brand names like Viagra® and Cialis® and compounded versions like sildenafil and tadalafil designed to improve sexual health and confidence.
Whether you’re looking to lose weight, optimize your hormones, improve performance, restore your hair, enhance longevity, or address sexual health concerns, our licensed medical providers create personalized treatment plans that fit your goals—all from the comfort of home.
He & She MD does not accept insurance at this time.
You may be able to submit a claim to your insurance carrier after paying He & She MD directly, but we do not provide superbills, nor do we communicate with insurance carriers. Patients may submit receipts independently; however, reimbursement is not guaranteed.
F&F Pharmacies Inc DBA Jungle Jim’s Pharmacy is located at 5484 Dixie Highway Fairfield, OH 45014. They can be contacted at (877) 858-3784. They are able to dispense medications and maintain a license in 44 US states. Unfortunately, they cannot dispense sterile compounds and do not have a license in the following US states: CALIFORNIA, NEVADA, NEW JERSEY, NORTH CAROLINA, TEXAS, MASSACHUSETTS, MISSISSIPPI, NEW HAMPSHIRE, WEST VIRGINIA, and DELAWARE.
He & She MD will continue to partner with both Specialty Medical Drugstore LLC (dba GoGoMeds) and F&F Pharmacies Inc (dba Jungle Jim’s Pharmacy) for prescription fulfillment.
Our clinical providers are Wasef Health, PC c/o Michael Wasef MD.
Contact: contact@wasef-health.com.
Office located at 5260 78th Ave N, PO Box 1697, Pinellas Park, FL,
For GLP-1s, He & She MD ships to all U.S. states except Louisiana.
For Longevity and HRT medications, we ship nationwide.
📦 We do not ship to PO Boxes.
📦 All packages are shipped discreetly.
All medication is dispensed by licensed U.S. FDA-registered pharmacies that meet strict quality and safety standards. State boards of pharmacy conduct inspections every 6–12 months, and sterile compound batches undergo required third-party testing.
Yes. Your information is fully encrypted and securely stored. Your health data is confidential, and only you and your clinician can access your medical information.
Have more questions? Send us a message.
Take the first step toward balanced hormones and feeling like yourself again.
