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Sermorelin Injection

Rx

Supports energy, lean muscle mass, and strength by encouraging the body to replenish its own growth hormone gradually — without the risks of synthetic HGH.

Starting at

$99 / mo
Frequently asked questions

How do you take Sermorelin Injection?

Sermorelin is taken as a subcutaneous injection into a fatty layer of tissue such as your thigh or abdomen. If you’re approved for a Sermorelin prescription, your provider will provide a tailored titration schedule and dosing instructions.

 

Is Sermorelin Injection safe?

Sermorelin is generally well tolerated with a minimal risk of side effects. Sermorelin is often considered safer than other HGH therapies because it works with the body’s natural systems to produce HGH, as opposed to direct HGH replacement. However, there are risks with any treatment. Please see important safety information for Sermorelin and consult your provider about the potential risks and benefits.

 

Is Sermorelin a steroid?

No, Sermorelin has a different mechanism of action than steroids.

Sermorelin is a peptide that mimics growth hormone-releasing hormone (GHRH), stimulating the pituitary gland in the brain to release more of the body’s natural human growth hormone (HGH).

Steroids mimic hormones directly, acting as a replacement without stimulating the body to release its own hormones. This increases the risk of hormone imbalance, mood disorders, liver damage, and other related side effects.

 

Usage instructions

Sermorelin Injections are self-injected 1-3 times per week, with or without food, according to your provider-guided titration schedule. If prescribed, a US-licensed provider will provide a tailored dosage schedule and specific treatment instructions with your care plan.

Side effects

The most common side effects of Sermorelin include:

  • Pain, redness, or irritation at the injection site
  • Face or neck flushing
  • Headache
  • Nausea

Side effects are usually mild and often go away on their own within a week or two.
For a full list of side effects, please review Healthline’s Sermorelin resources.

Potential drug interactions

Sermorelin has no known major drug interactions, but may have the following interactions with certain drugs:

  • Glucocorticoids (prednisone)
    May blunt growth hormone (GH) release
  • Oral estrogens
    May increase IGF-1 resistance
  • Insulin or sulfonylureas
    May alter glycemic control
  • Somatostatin analogs
    May antagonize Sermorelin’s effects
  • Dopamine antagonists
    May disrupt human growth hormone (HGH) regulation
  • GABAergic meds
    May reduce pulsatility of HGH release
  • Beta blockers (Metoprolol or Propranolol)
  • Other secretagogues/peptides
    May result in unsafe levels of HGH

Other important safety information

Sermorelin is only for users who are at least 30 years old. Customers under 30 should explore other longevity solutions.

Your provider may ask you for additional information if you have one of the following conditions:

  • Hypothyroidism
    Untreated hypothyroidism can impair a user’s growth hormone (GH) response. Users with hypothyroidism may be asked to show that their condition is treated and managed
  • Hyperglycemia or diabetes
    Taking Sermorelin with untreated hyperglycemia or diabetes may further impair glycemic control. Users with hyperglycemia or diabetes may be asked to show that their condition is treated and managed

Sermorelin should not be used by anyone with moderate to severe liver dysfunction or kidney disease.

Do not use Sermorelin if you have an active cancer, or if you have had cancer within the last two years.

Do not use Sermorelin if you are pregnant, breastfeeding, or planning to become pregnant or breastfeed. If you become pregnant while taking Sermorelin, consult your provider before continuing with your next dose.

Though rare, allergic reactions to Sermorelin are still possible. If you notice any shortness of breath or swelling around your face, tongue, or throat after using Sermorelin, stop use and contact emergency services right away. Mild allergic reactions around the injection site are normal and not cause for emergency.

As with any prescription medication, the dose prescribed is for you and you alone. Do not, under any circumstances, allow anyone else to use your Sermorelin.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What is Sermorelin?

(ser-mor-luhn)

After age 30, human growth hormone (HGH) levels decline by up to 15%1 per decade, impacting everything from metabolism and muscle tone to recovery and sleep quality.2

Unlike other synthetic options that override the system, Sermorelin works with the body, stimulating natural HGH production from the brain to potentially support lean muscle mass, energy, and metabolism.2

Growth hormone levels drop up to 45% between age 30 and 60.8

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How Sermorelin works

Many patients begin noticing early changes in sleep quality and energy.

Consistent use supports ongoing natural growth hormone stimulation.

Some patients report improved recovery and more restorative sleep.

As body composition shifts, users may notice benefits in metabolic health, mood, and overall quality of life.2

Continued treatment is intended to support long-term wellness as part of an ongoing care plan.

Results you can feel
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reported better muscle building

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reported noticeable benefits by second check-in

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reported better moods

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felt more energized

Tested for quality, backed by science

We only work with US-licensed pharmacies that prioritize strict quality control standards, so you can count on purity, potency, and safety.

The science of Sermorelin

Sermorelin is an analog of growth hormone-releasing hormone (GHRH). Unlike direct HGH therapy, Sermorelin signals the pituitary gland to release human growth hormone (HGH) in a pulsed, physiological rhythm, supporting a more balanced approach to hormone therapy.1 7

Research suggests Sermorelin may help naturally restore essential hormones, supporting the ability to build muscle, restore energy, and improve overall quality of life.2 3

Expert care that starts with you

Our in-house care team with 199+ years of combined expertise meets you where you are, and gets you to where you want to be.

$99/first month

Applies to 3-month plan billed in full ($149/mo after)

What's included

Made for your biology

No two people age the same way, so no two treatments are exactly the same. Your plan is guided by your symptoms, your biology and your priorities. It’s a whole “you” approach to living a better, longer life.

How It Works

Choosing how you age starts here

1

Clinician-Led

Connect with a clinician

Connect with one of our US-licensed medical providers to make sure treatment is right for you. 100% online — no in-person visit required.

2

Fast, Discreet Shipping

Get your discreet shipment

If approved, your treatment is compounded by a US-licensed pharmacy partner and shipped discreetly to your door.

3

100% Online

Receive continuous support

With our care team, unlimited provider messaging, easy refills, and ongoing dosage adjustments, your care evolves with you.

Frequently asked questions

What is He & She MD?

He & She MD is a modern telehealth clinic offering treatments across Weight Loss, Longevity, Hormone Therapy, and Performance Health. Getting started is simple: complete a quick 5-minute medical quiz, and a licensed U.S. clinician will review your information. If appropriate, your medication is shipped directly — and discreetly — to your door.

Our care process is designed to make treatment fast, safe, and convenient:

  1. Complete a 5-minute medical quiz so your clinician can understand your goals and medical history.
  2. A licensed, board-certified U.S. physician or DO reviews your questionnaire.
  3. If clinically appropriate, your prescription is approved and your medication is shipped directly to your home through one of our licensed pharmacy partners.
  4. You receive unlimited messaging access to your clinician for ongoing support, dosage adjustments, and guidance — keeping you on track with your personalized treatment plan.

💳 You are only charged if the medication is prescribed.

(If you are not a candidate, you pay nothing.)

He & She MD provides personalized care across six core treatment categories, with every treatment plan reviewed by a licensed healthcare provider and customized to your individual health goals.

 

Weight Loss
Medical weight loss programs featuring GLP-1 medications, including compounded Semaglutide and Tirzepatide (where appropriate), as well as FDA-approved brand medications such as Wegovy®, Ozempic®, Zepbound®, and Mounjaro® when clinically appropriate and available.

 

Longevity
Advanced wellness therapies designed to support healthy aging, energy, recovery, and overall vitality, including NAD+, Glutathione, Sermorelin, and other longevity-focused peptide therapies.

 

Hormone Therapy
Personalized hormone optimization for men and women, including treatments such as testosterone support, estradiol, progesterone, and other evidence-based hormone therapies designed to restore balance and improve quality of life.

 

Performance Health
Treatments designed to support men’s health, energy, strength, recovery, and sexual performance, including Enclomiphene, and Testosterone Replacement Therapy (when appropriate), and other physician-directed therapies.

 

Hair Growth
Personalized hair restoration treatments for both men and women, including oral and topical medications such as Finasteride, Minoxidil, combination therapies, and other clinically appropriate hair loss solutions.

 

Sexual Health
Discreet, evidence-based treatments for sexual wellness, including erectile dysfunction therapies, libido support, and other personalized solutions including brand names like Viagra® and Cialis® and compounded versions like sildenafil and tadalafil designed to improve sexual health and confidence.

Whether you’re looking to lose weight, optimize your hormones, improve performance, restore your hair, enhance longevity, or address sexual health concerns, our licensed medical providers create personalized treatment plans that fit your goals—all from the comfort of home.  

He & She MD does not accept insurance at this time.

You may be able to submit a claim to your insurance carrier after paying He & She MD directly, but we do not provide superbills, nor do we communicate with insurance carriers. Patients may submit receipts independently; however, reimbursement is not guaranteed.

F&F Pharmacies Inc DBA Jungle Jim’s Pharmacy is located at 5484 Dixie Highway Fairfield, OH 45014. They can be contacted at (877) 858-3784. They are able to dispense medications and maintain a license in 44 US states. Unfortunately, they cannot dispense sterile compounds and do not have a license in the following US states: CALIFORNIA, NEVADA, NEW JERSEY, NORTH CAROLINA, TEXAS, MASSACHUSETTS, MISSISSIPPI, NEW HAMPSHIRE, WEST VIRGINIA, and DELAWARE.

He & She MD will continue to partner with both Specialty Medical Drugstore LLC (dba GoGoMeds) and F&F Pharmacies Inc (dba Jungle Jim’s Pharmacy) for prescription fulfillment.

Our clinical providers are Wasef Health, PC c/o Michael Wasef MD.

Contact: contact@wasef-health.com.

Office located at 5260 78th Ave N, PO Box 1697, Pinellas Park, FL,

For GLP-1s, He & She MD ships to all U.S. states except Louisiana.

For Longevity and HRT medications, we ship nationwide.

📦 We do not ship to PO Boxes.

📦 All packages are shipped discreetly.

All medication is dispensed by licensed U.S. FDA-registered pharmacies that meet strict quality and safety standards. State boards of pharmacy conduct inspections every 6–12 months, and sterile compound batches undergo required third-party testing.

Yes. Your information is fully encrypted and securely stored. Your health data is confidential, and only you and your clinician can access your medical information.

Have more questions? Send us a message.